MyBioSource.com's DR1 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The DR1 Antibody (Center) was generated using DR1, and NC2 as the antigen and it reacts with Human, Mouse, and Rat.
Description
This gene encodes a TBP- (TATA box-binding protein)
associated phosphoprotein that represses both basal and activated
levels of transcription. The encoded protein is phosphorylated in
vivo and this phosphorylation affects its interaction with TBP.
This protein contains a histone fold motif at the amino terminus, a
TBP-binding domain, and a glutamine- and alanine-rich region. The
binding of DR1 repressor complexes to TBP-promoter complexes may
establish a mechanism in which an altered DNA conformation,
together with the formation of higher order complexes, inhibits the
assembly of the preinitiation complex and controls the rate of RNA
polymerase II transcription